Clinical Data Stewardship Projects

Our clinical data stewardship projects are helping investigators in several domains improve clinical outcomes and address health disparities.

Realizing Accelerated Progress, Investigation, Implementation, and Dissemination in Learning Health Systems (RAPID-LHS) Center 

Major Goals: This P30 application, funded by AHRQ and PCORI, aims to establish a center that supports the development of faculty health scientists in learning health systems (LHS) research. The center will also provide resources for the evaluation of LHS initiatives, aligning with AHRQ’s vision to improve health care quality in America. 

The Mid-South Clinical Data Research Network/PCORnet 

Major Goals: This initiative, supported by PCORI, aims to establish a Clinical Data Research Network (CDRN) comprising three large health systems. These include the Vanderbilt Health System, Vanderbilt Healthcare Affiliated Network (VHAN), and a partnership with Greenway Medical Technologies. The network will facilitate research access to millions of patient records in the mid-South region. 

Engaging Cooperative Sites for Trial Acceleration, Trust, Innovation, and Capability (ECSTATIC) 

Major Goals: ECSTATIC aims to enhance institutional preparedness for multisite research, with a focus on engaging Historically Black Colleges and Universities (HBCUs) and other non-CTSA institutions. The project seeks to broaden inclusivity in research and strengthen technical infrastructure for response to Expression of Interest (EOI) requests. 

The Sepsis ClinicAl Resource And Biorepository (SCARAB) Project 

Major Goals: SCARAB aims to revolutionize clinical research in sepsis by creating a comprehensive clinical dataset linked to longitudinal biospecimens and outcomes data. The project, funded by NIH, aligns with the NIGMS Priorities in Sepsis Research initiative to improve understanding and treatment of sepsis. 

Sharing Electronic Health Records (EHR) for research

Major Goal: To develop natural language processing pipeline to identify social determinant health (SDoH) factors for patients with substance use disorders.

Social Determinant of Health on Cardiovascular Disease Among Black Women with Substance Use Disorders

Major Goal: To explore social determinant of health factors among Black women with substance use disorders and its association with cardiovascular disease.

A Retrospective Study to Examine the Correlation between High Cholesterol and Substance Use Disorder

Major Goal: To examine the correlation between high cholesterol and substance use disorder.

A Retrospective Study to Examine the Correlation between High Cholesterol and Substance Use Disorder

Major Goal: Evaluate the impact of COVID pandemic on patients with substance use disorder with comorbid mental health problem, especially for the pregnant women within underserved population.

The RCMI Program in Health Disparities Research at Meharry Medical College – Supplement – Institutional Data Science

Major Goal: To enhance Meharry’s research capabilities in AI/ML by (1) creating AI/ML infrastructure in the cloud and on-site, (2) developing data science competencies among Meharry faculty, staff, and students through comprehensive training program, and (3) fostering collaboration and innovation in data science through partnerships and community.